Additionally, the indole Main is substituted at R3 with a carbonyl group that's also bonded to a napthalene moeity. Napthalene can be a bicyclic framework of two fused benzene rings. This carbonyl bridge of JWH-018 classifies it like a ketone. JWH-018 is surely an analog of THJ-018, through which the core indazole framework is substituted using an